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ML115

SKU: orb1304070

Description

ML115 is a potent and selective STAT3 activator (EC50 = 2.0 nM) that shows no activity against STAT1 or NFκB. This tool compound is valuable for investigating STAT3-dependent signaling pathways in cancer and immunology research, both in cellular assays and in vivo models.

Research Area

Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number912798-42-6
MW322.74
Purity99.97% (May vary between batches)
FormulaC15H15ClN2O4
SMILESCOc1cc(NC(=O)c2cc(on2)C2CC2)c(OC)cc1Cl
TargetSTAT
Solubility10% DMSO+90% Corn Oil:1 mg/mL (3.1 mM);DMF:25 mg/mL (77.46 mM);DMSO:22.73 mg/mL (70.43 mM);Ethanol:0.1 mg/mL (0.31 mM)

Bioactivity

Target IC50
STAT3:2.0 nM

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

STAT3, ML 115, ML115, ML-115
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.

Key Properties

No computed properties available.

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Protocol Information

ML115 (orb1304070)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 mg
$ 140.00
5 mg
$ 280.00
1 ml x 10 mM (in DMSO)
$ 310.00
10 mg
$ 420.00
25 mg
$ 710.00
50 mg
$ 970.00
100 mg
$ 1,290.00
200 mg
$ 1,720.00
500 mg
$ 2,520.00
DispatchUsually dispatched within 3-5 working days
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