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Monoamine Oxidase B inhibitor 4

SKU: orb2564711

Description

Compound 1l is a potent and selective hMAO-B inhibitor (IC50 = 8.3 nM) with anti-neuroinflammatory activity. It reduces LPS- and Aβ1-42-induced NO, TNF-α, and IL-1β release and protects against Aβ(1-42) cytotoxicity in vitro, supporting research in neurodegeneration and neuroinflammation.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number424794-91-2
MW324.16
FormulaC15H11Cl2NO3
SMILESO=C(NC1=CC=C(Cl)C(Cl)=C1)C2=CC=C3OCCOC3=C2
TargetMonoamine Oxidase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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Monoamine Oxidase B inhibitor 4 (orb2564711)

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