Moringin

SKU: orb1297087

Description

Moringin is a bioactive isothiocyanate derived from Moringa oleifera seeds via enzymatic hydrolysis of glucoMoringin. It exhibits documented anti-inflammatory and antioxidant activities, making it a relevant compound for research in cellular oxidative stress models and in vivo studies on inflammation.

Research Area

Cell Biology, Immunology & Inflammation, Metabolism Research, Molecular Biology, Neuroscience, Pharmacology & Drug Discovery, Protein Biochemistry, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

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Key Properties

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CAS Number	73255-40-0
MW	311.35
Purity	99.88%
Formula	C₁₄H₁₇NO₅S
SMILES	O([C@H]1[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O1)C2=CC=C(CN=C=S)C=C2
Target	Nrf2,COX,p53,GSK-3,gp120/CD4,Bcl-2 Family,TNF,TRP/TRPV Channel,IL Receptor,PPAR,Caspase,Wnt/beta-catenin
Solubility	10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.42 mM);DMSO:62.5 mg/mL (200.74 mM)

Bioactivity

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In Vitro

Moringin modulates neuroinflammation via the β-catenin-PPARγ axis and activates Wnt canonical pathway by inhibiting GSK3β in a mouse model of experimental autoimmune encephalomyelitis. Moringin is effective in inducing apoptosis through p53 and Bax activation and Bcl-2 inhibition. Moringin demonstrates the antitumor efficacy in human malignant astrocytoma cells. The combination of Cannabidiol (5μM) and Moringin (5μM) has anti-inflammatory, antioxidative, and anti-apoptotic effects.

Storage & Handling

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Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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COX, beta-catenin, betacatenin, CD4, Bcl-2, bcatenin, Caspase, IL Receptor, ILReceptor, Moringin, gp120, gp120/CD4, GSK-3, GSK3, Nrf2, p53, βcatenin, TNF-α, Wnt/betacatenin, Wnt/β-catenin, Wnt/b-catenin, Wnt, PPAR

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Compound Identifiers

PubChem CID

153557 ↗

Key Properties

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No computed properties available.

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Moringin

Description

Research Area

Images & Validation

Key Properties

Bioactivity

Storage & Handling

Alternative Names

Quality Guarantee

Compound Identifiers

Key Properties

Documents Download

Request a Document

Protocol Information

Moringin (orb1297087)

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