Moscatin

SKU: orb1684399

Description

Moscatin (Plicatol, 4-methoxyphenanthrene-2,5-diol) is a natural diphenyl compound from Dendrobium nobile Lindl. It exhibits antiplatelet activity by inhibiting arachidonic acid-induced aggregation and shows antifungal potential against Candida albicans by downregulating virulence genes like ERG and ALS. This makes it a candidate for research in cardiovascular and microbiological fields.

Research Area

Metabolism Research, Signal Transduction

Images & Validation

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Key Properties

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CAS Number	108335-06-4
MW	240.25
Purity	99.89%
Formula	C₁₅H₁₂O₃
SMILES	OC=1C=C(OC)C2=C(C=CC=3C=CC=C(O)C32)C1
Target	HSP,Platelet aggregation

Bioactivity

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Target IC50	AA-induced platelet aggregation:37.2  μM
In Vivo	In mouse infection models (systemic and OPC), moscatin injection (20 μg/ml, 200 μL) significantly reduce the pathogenicity of andida albicans SC5314. Moscatin restored gut microbiota balance in andida albicans-infected mice, increasing beneficial bacteria levels and reducing fungal burden. Read more...
In Vitro	Moscatin inhibits washed rabbit platelet aggregation in a concentration dependent manner, showing complete Inhibition of AA- and collagen-induced aggregation at 100 μg/ml. Moscatin IC50 against AA-induced aggregation is 37.2 μM, likely by interfering with thromboxane A₂ formation. Read more...

Storage & Handling

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Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Plicatol, Moscatin, 4-methoxyphenanthrene-2,5-diol

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Compound Identifiers

PubChem CID

194774 ↗

Key Properties

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No computed properties available.

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Moscatin

Description

Research Area

Images & Validation

Key Properties

Bioactivity

Storage & Handling

Alternative Names

Quality Guarantee

Compound Identifiers

Key Properties

Documents Download

Request a Document

Protocol Information

Moscatin (orb1684399)

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