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Moscatin

SKU: orb1684399

Description

Moscatin (Plicatol, 4-methoxyphenanthrene-2,5-diol) is a natural diphenyl compound from Dendrobium nobile Lindl. It exhibits antiplatelet activity by inhibiting arachidonic acid-induced aggregation and shows antifungal potential against Candida albicans by downregulating virulence genes like ERG and ALS. This makes it a candidate for research in cardiovascular and microbiological fields.

Research Area

Metabolism Research, Signal Transduction

Images & Validation

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Moscatin

Key Properties

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CAS Number108335-06-4
MW240.25
Purity99.89% (May vary between batches)
FormulaC15H12O3
SMILESOC=1C=C(OC)C2=C(C=CC=3C=CC=C(O)C32)C1
TargetPlatelet aggregation,HSP

Bioactivity

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Target IC50
AA-induced platelet aggregation:37.2  μM
In Vivo
In mouse infection models (systemic and OPC), moscatin injection (20 μg/mL, 200 μL) significantly reduced the pathogenicity of Candida albicans SC5314 . Moscatin restored gut microbiota balance in Candida albicans-infected mice, increasing beneficial bacteria levels and reducing fungal burden .
In Vitro
Moscatin inhibits washed rabbit platelet aggregation in a concentration-dependent manner, showing complete inhibition of AA- and collagen-induced aggregation at 100 μg/mL. Moscatin IC₅₀ against AA-induced aggregation is 37.2 μM, likely by interfering with thromboxane A₂ formation .

Storage & Handling

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Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

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Plicatol, Moscatin, 4-methoxyphenanthrene-2,5-diol
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.

Compound Identifiers

PubChem CID
194774 ↗

Key Properties

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No computed properties available.

Protocol Information

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Available Sizes

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5 mg
$ 470.00
DispatchUsually dispatched within 5-10 working days
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