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MOSLOFLAVONE

SKU: orb1220685

Description

MOSLOFLAVONE showed promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 0.71 μM and 7.8 μM respectively.

Images & Validation

Key Properties

CAS Number740-33-0
MW298.29
Purity>98% (HPLC)
FormulaC17H14O5
SMILESCOc1cc2oc(cc(=O)c2c(O)c1OC)-c1ccccc1
TargetTNF
SolubilityIn Vitro: DMSO : 50 mg/mL (167.62 mM)

Bioactivity

In Vitro
Mosloflavone shows promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 16.4 uM and 6.4 uM, respectively; inhibits TNF-α, IL-1β and iNOS levels in the supernatant of mouse macrophage cell line J774A as a dose-dependent manner, it also can be used as a starting point to discover lead structures for treatment of inflammatory and immunomodulatory diseases.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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MOSLOFLAVONE (orb1220685)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

5 mg
$ 460.00
10 mg
$ 760.00
25 mg
$ 1,180.00
50 mg
$ 1,540.00
100 mg
$ 2,110.00
500 mg
$ 4,180.00