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MOSLOFLAVONE

SKU: orb1301498

Description

MOSLOFLAVONE

Research Area

Cell Biology, Immunology & Inflammation, Infectious Disease & Virology

Images & Validation

Key Properties

CAS Number740-33-0
MW298.29
Purity99.99%
FormulaC17H14O5
SMILESCOc1cc2oc(cc(=O)c2c(O)c1OC)-c1ccccc1
TargetIL Receptor,Virus Protease,Antibacterial,TNF
SolubilityDMSO:11 mg/mL (36.88 mM)

Bioactivity

Target IC50
IL-1β:7.8μM|TNF-α:0.71μM
In Vitro
MOSLOFLAVONE showed promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 0.71 μM and 7.8 μM, respectively,and also showed dose-dependent inhibition of TNF-α, IL-1β and iNOS levels in the supernatant of mouse macrophage cell line J774A. MOSLOFLAVONE can be used as a starting point to discover lead structures for treatment of inflammatory and immunomodulatory diseases.

Storage & Handling

Storagekeep away from direct sunlight,keep away from moisture,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Bacterial, biocide, inhibit, Inhibitor, P. aeruginosa, HEV, HEVs, HRVs, HRV, IL Receptor, IL-1β, ILReceptor, MOSLOFLAVONE, Enterovirus 71, Enterovirus, EV-71, TNF-α, Rhinovirus, VirusProtease, Virus Protease

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    740-33-0

    298.29

    C17H14O5

    1 g, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg
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Key Properties

No computed properties available.

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MOSLOFLAVONE (orb1301498)

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% DMSO +
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% Tween 80 +
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Available Sizes

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5 mg
$ 80.00
10 mg
$ 110.00
25 mg
$ 150.00
50 mg
$ 200.00
100 mg
$ 270.00
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