Mouse IRAK4 Protein, His Tag (active enzyme)

SKU: orb3158026

Description

This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.

Images & Validation

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Application Notes	This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 52.9 kDa.

Key Properties

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Expression System	InsectCells
Target	IRAK4
Reactivity	Mouse
Tag	N-10×His
Molecular Weight	52.9 kDa
Expression Region	Met 1 - Ala 459
Endotoxins	1.0 EU per μg
Conjugation	Unconjugated

Storage & Handling

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Storage	-70°C
Form/Appearance	Liquid
Buffer/Preservatives	50 mM Tris, 150 mM NaCl, pH 7.5
Expiration Date	6 months from date of receipt.
Dry Ice Shipping	Please note: This product requires shipment on dry ice. A dry ice surcharge will apply.
Disclaimer	For research use only

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Quick Database Links

Gene Symbol

IRAK4

UniProt

Q8R4K2

RefSeq:Q8R4K2

UniProt Details

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No UniProt data available

NCBI Reference Sequences

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Associated Accession Numbers

Curated reference sequences for the gene transcript and protein product

RefSeq	Q8R4K2

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