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MST-312

SKU: orb1303124

Description

MST-312

Research Area

Molecular Biology

Images & Validation

Key Properties

CAS Number368449-04-1
MW380.35
Purity99.68% (May vary between batches)
FormulaC20H16N2O6
SMILESOc1cccc(C(=O)Nc2cccc(NC(=O)c3cccc(O)c3O)c2)c1O
TargetTelomerase
SolubilityH2O:Insoluble;DMSO:250 mg/mL (657.29 mM);2% DMSO+40% PEG300+5% Tween 80+ 53% Saline:5 mg/mL (13.15 mM)

Bioactivity

In Vitro
In U-266 cells, MST-312 (2 μM) upregulates the pro-apoptotic gene Bax and down-regulates the anti-apoptotic gene Bcl-2 and suppresses the expression of c-Myc and hTERT genes. MST-312 (2-8 μM) reduces cellular viability in a dose dependent and time-dependent manner. MST-312 (2-8 μM) induces cell apoptosis in a dose-dependent manner.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

gallate, EGCG, epigallocatechin, myeloma, multiple, MST312, MST-312, MST 312, inhibit, Inhibitor, derivative, cancer, tea, Telomerase Inhibitor IX, Telomerase
Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

2 mg
$ 70.00
5 mg
$ 90.00
1 ml x 10 mM (in DMSO)
$ 90.00
10 mg
$ 120.00
25 mg
$ 190.00