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MTX-531

SKU: orb2564258

Description

MTX-531 is a selective inhibitor of EGFR and PI3K with IC50 of 14.7 nM and 1.1-233 nM (PI3Kα, PI3Kβ...), respectively. It also acts as a weak agonist of PPARγ, with an EC50 of 3.4 μM in 293H cells.

Research Area

Cardiovascular Research, Metabolism Research, Molecular Biology, Signal Transduction

Images & Validation

Key Properties

CAS Number2791417-66-6
MW453.94
FormulaC22H20ClN5O2S
SMILESN([C@H](C)C1=CC=CC=C1)C=2C3=C(C=CC(=C3)C=4C=C(NS(C)(=O)=O)C(Cl)=NC4)N=CN2
TargetEGFR,PPAR,PI3K

Storage & Handling

Storage-20°C
DisclaimerFor research use only
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MTX-531 (orb2564258)

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