N-acetyl-5-Aminosalicylic Acid

SKU: orb1694382

Description

N-Acetyl-5-Aminosalicylic Acid is the primary acetylated metabolite of the anti-inflammatory drug mesalazine. It is utilized in research to study drug metabolism, pharmacokinetics, and the mechanisms of mesalazine in models of inflammatory bowel disease, both in vitro and in vivo.

Research Area

Metabolism Research

Images & Validation

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Key Properties

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CAS Number	51-59-2
MW	195.17
Purity	99.89% (May vary between batches)
Formula	C₉H₉NO₄
SMILES	O=C(O)C1=CC(=CC=C1O)NC(=O)C
Target	Drug Metabolite
Solubility	Methanol:8 mg/mL (40.99 mM);DMSO:40 mg/mL (204.95 mM)

Bioactivity

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In Vitro	N-acetyl-5-Aminosalicylic Acid is a PP2A inhibitor. N-acetyl-5-Aminosalicylic Acid can be used in the study of ulcerative colitis. The inhibitory effect of flavonoids on the effluents of N-acetyl-5-Aminosalicylic Acid formed in Caco-2 cells. Read more...

Storage & Handling

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Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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N acetyl 5 Aminosalicylic Acid, N-Acetyl mesalazine, Nacetyl5Aminosalicylic Acid, N-acetyl-5-Aminosalicylic Acid, N-acetyl-ASA

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Compound Identifiers

PubChem CID

65512 ↗

Key Properties

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No computed properties available.

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