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nAChR agonist CMPI hydrochloride

SKU: orb1691069

Description

CMPI hydrochloride is a potent and selective positive allosteric modulator (PAM) targeting the α4:α4 interface of nicotinic acetylcholine receptors. It enhances ACh responses at (α4)3(β2)2 nAChRs (EC50 0.26 μM) and serves as a valuable research tool for studying nicotine dependence and neuropsychiatric disorders associated with cholinergic hypofunction in both in vitro and in vivo models.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2250025-94-4
MW379.29
FormulaC18H20Cl2N4O
SMILESCl.Cc1c(cnn1C1CCNCC1)-c1cc(no1)-c1ccccc1Cl
TargetOthers,AChR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information