Nanatinostat TFA

SKU: orb1738370

Description

Nanatinostat (CHR-3996) is an oral, second-generation HDAC inhibitor with antineoplastic potential. It promotes histone hyperacetylation and gene expression changes leading to cell cycle arrest and apoptosis, showing enhanced effects on HSP70 and Bcl-2 compared to earlier inhibitors. It has been investigated in preclinical models for hematological and solid tumors.

Research Area

Cell Biology, Epigenetics & Chromatin, Molecular Biology

Images & Validation

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Key Properties

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CAS Number	1256448-48-2
MW	508.43
Formula	C₂₂H₂₀F₄N₆O₄
SMILES	OC(=O)C(F)(F)F.[H][C@@]12CN(C[C@]1([H])[C@H]2NCc1ccc2cc(F)ccc2n1)c1ncc(cn1)C(=O)NO
Target	Others,HDAC,Apoptosis

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

131888677 ↗

Key Properties

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No computed properties available.

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