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Necrostatin-1

SKU: orb1225065

Description

Necrostatin-1 is a specific RIP1 inhibitor and inhibits TNF-α-induced necroptosis with EC50 of 490 nM.

Images & Validation

Key Properties

CAS Number4311-88-0
MW259.33
Purity>98% (HPLC)
FormulaC13H13N3OS
SMILESO=C(C(CC1=CNC2=C1C=CC=C2)N3)N(C)C3=S
TargetTNF
SolubilityDMSO: 51 mg/mL warmed (196.66 mM)

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Nec-1

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Necrostatin-1 (orb1225065)

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% DMSO +
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500 mg
5 mg
$ 70.00
10 mg
$ 90.00
25 mg
$ 140.00
50 mg
$ 220.00
100 mg
$ 270.00
200 mg
$ 380.00