NEDD5 (C1) Antibody, Rabbit Polyclonal

SKU: orb67228

Description

Rabbit polyclonal to NEDD5.Septin-2 (NEDD5) is a filament-forming cytoskeletal GTPase that belongs to the septin family. It isrequired for normal organization of the actin cytoskeleton. NEDD5 plays a role in the biogenesis ofpolarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitatingefficient vesicle transport. NEDD5 is required for the progression through mitosis. During anaphase,NEDD5 may be required for chromosome segregation and spindle elongation. NEDD5 plays a role inciliogenesis and collective cell movements. It may also play a role in the internalization of 2intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri.

Research Area

Stem Cell & Developmental Biology

Images & Validation

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Tested Applications	WB
Dilution Range	WB:1:500-1:3000
Reactivity	Human

Key Properties

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Host	Rabbit
Clonality	Polyclonal
Immunogen	C-terminal region of human NEDD5
Molecular Weight	41
Purity	Affinity purification
Conjugation	Unconjugated

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Buffer/Preservatives	0.01% NaN3
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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anti-NEDD5 antibody,anti-Septin2 antibody,anti-Neural precursor cell expressed developmentally downregulated protein 5 antibody,anti-NEDD5 antibody,anti-DIFF6 antibody,anti- KIAA0158 antibody

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Western blot analysis of total cell extracts from human Jurkat(Lane1),mouse thymus(Lane2) and mouse brain(Lane3) using NEDD5 antibody

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UniProt

Q15019

UniProt Details

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No UniProt data available

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Protocol Information

Western Blot (IB, immunoblot)

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