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NH2-c[X-R-L-S-X]-K-G-P-(D-1Nal)

SKU: orb1981234

Description

Compound 39 (NH2-c[X-R-L-S-X]-K-G-P-(D-1Nal)) is a potent agonist of the APJ receptor, possessing a K i value of 0.6 nM. It is capable of activating Gαi1, with an EC 50 of 0.8 nM, and of recruiting β-arrestin2, with an EC 50 of 31 nM. Furthermore, this compound demonstrates extended effects on cardiac function.

Images & Validation

Key Properties

CAS Number2891469-80-8
MW1020.18
FormulaC49H73N13O11
TargetApelin receptor,Others

Storage & Handling

Storage-20°C
DisclaimerFor research use only
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Protocol Information

NH2-c[X-R-L-S-X]-K-G-P-(D-1Nal) (orb1981234)

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