NLRP3 Rabbit Polyclonal Antibody

SKU: orb1675365

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Description

Research Area

Cancer Research, Growth Factors, Inflammation, Inflammatory Mediators, Macrophage, NF-kB Signalling Pathway

Images & Validation

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Item 1 of 1

Tested Applications	WB
Dilution Range	WB=1:500-2000
Reactivity	Human

Related Conjugates & Formulations

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Key Properties

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Antibody Type	Primary Antibody
Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Immunogen	Recombinant human NLRP3 (937-1036/1036aa)
Target	NLRP3
Molecular Weight	114 kDa
Purification	Affinity purified by Protein A
Conjugation	Unconjugated

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Form/Appearance	Liquid
Buffer/Preservatives	0.01M TBS (pH7.4) with 1% rAlbumin, 0.02% Proclin300 and 50% Glycerol.
Concentration	1mg/ml
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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LRR and PYD domains-containing protein 3; AGTAVPRL; AII/AVP antibody Angiotensin/vasopressin receptor AII/AVP like; Angiotensin/vasopressin receptor AII/AVP-like; C1orf7; Caterpiller protein 1.1; CIAS 1; CIAS1; CLR1.1; Cold autoinflammatory syndrome 1; Cold autoinflammatory syndrome 1 protein; Cryopyrin; Familial cold autoinflammatory syndrome; FCAS; FCU; Muckle-Wells syndrome; MWS; NACHT; NACHT LRR and PYD containing protein 3; NALP 3; NALP3; NALP3_HUMAN; NLRP3; PYPAF 1; PYPAF1 antibody PYRIN containing APAF1 like protein 1; PYRIN-containing APAF1-like protein 1.

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Sample: Lane 1: Recombinant human NALP3 protein, His, Primary: Anti-NLRP3 (orb1675365) at 1/1000 dilution, Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution, Predicted band size: 114 kDa, Observed band size: 11 kDa.

Quick Database Links

Gene Symbol

NLRP3

UniProt

Q96P20

UniProt Details

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No UniProt data available

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Datasheet

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Protocol Information

Western Blot (IB, immunoblot)

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Find More Protocols

You-Cheng Hseu 1 2 3 4, Yu-Fang Tseng 5, Jhih Ke-Hseu 6, Sudhir Pandey 1, Siang-Jyun Chen 5, Kai-Yuan Lin 7 8, Hsueh-Wei Chang 9, Tzong-Der Way 10, Chuan-Chen Lee 2, Jhih-Hsuan Hseu 11, Hsin-Ling Yang 5 Dihydromikanolide Inhibits ROS-Mediated NLRP3 Inflammation via Antioxidant Nrf2 Activation and Mitophagy Induction in LPS/ATP-Stimulated Macrophages J Cell Mol Med, (2025)

PubMed: 40857065