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N,N'-Diacetyl-L-cystine

SKU: orb1307983

Description

N,N'-Diacetyl-L-cystine (DiNAC) is an orally active, immunomodulating disulfide dimer of N-acetylcysteine. It exhibits antiatherosclerotic effects in WHHL rabbit models and modulates contact sensitivity/delayed-type hypersensitivity reactions in rodent studies, supporting research in immunology and cardiovascular disease.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number5545-17-5
MW324.37
Purity98.76%
FormulaC10H16N2O6S2
SMILESCC(=O)N[C@@H](CSSC[C@H](NC(C)=O)C(O)=O)C(O)=O
TargetAmino Acids and Derivatives,Others
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.17 mM);DMSO:15 mg/mL (46.24 mM)

Bioactivity

In Vivo
N,N'-Diacetyl-L-cystine (DiNAC; 0-973.11 μg/kg; p.o.; daily; for 12 weeks; WHHL rabbits) treatment reduces thoracic aorta atherosclerosis by 50%, without affecting plasma lipid levels.

Storage & Handling

Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

N,N'DiacetylLcystine, N,N'-Diacetyl-L-cystine, N,N' Diacetyl L cystine, modulator, Immunomodulator, immunomodulatory, inhibit, Inhibitor, Atherogenesis, (Ac-Cys-OH)2, disulphide, dimer, DiNAC, rodents

Similar Products

  • N,N'-Diacetyl-L-cystine [orb1940707]

    >98% (HPLC)

    5545-17-5

    324.37

    C10H16N2O6S2

    100 mg, 1 g, 500 mg, 200 mg
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Key Properties

No computed properties available.

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N,N'-Diacetyl-L-cystine (orb1307983)

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1 ml x 10 mM (in DMSO)
$ 70.00
200 mg
$ 80.00
500 mg
$ 100.00
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