NOD2 antagonist 1

SKU: orb1686954

Description

NOD2 antagonist 1 (compound 32) is a selective small molecule inhibitor of NOD2 with an IC50 of 5.23 µM. It effectively suppresses MDP-induced IL-8 secretion in THP-1 cells and inhibits the production of IL-6, IL-10, and TNF-α in PBMCs, making it a useful tool for studying NOD2-mediated inflammatory pathways in vitro.

Research Area

Immunology & Inflammation

Images & Validation

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Key Properties

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CAS Number	2411441-54-6
MW	474.57
Purity	98.83% (May vary between batches)
Formula	C₂₆H₂₆N₄O₃S
SMILES	C(C(NC=1C=C2C(=CC1)CCC2)=O)N3C=4C(N=C3CCNS(=O)(=O)C5=CC=CC=C5)=CC=CC4
Target	NOD-like Receptor (NLR),Others

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

162672282 ↗

Key Properties

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No computed properties available.

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