Cart summary

You have no items in your shopping cart.

Nomilin

SKU: orb1222891

Description

Nomilin is an inducer of phase II detoxifying enzymes, showing anti-proliferative active on cultured human breast cancer cells.(In Vitro):Nomilin treatment significantly mitigated cell death and decreased lactate dehydrogenase (LDH) release and ROS production in SH-SY5Y cells induced by oxygen-glucose deprivation (OGD), which was almost abolished by Nrf2 knockdown.(In Vivo):Nomilin attenuated blood-brain barrier (BBB) disruption in MCAO rats, which might be associated with alleviating the loss of tight junction proteins, including ZO-1 and occludin-5.

Images & Validation

Key Properties

CAS Number1063-77-0
MW514.57
Purity>98% (HPLC)
FormulaC28H34O9
SMILESCC(=O)OC5CC(=O)O[C@@](C)(C)[C@@H]6CC(=O)[C@]3(C)[C@H](CC[C@@]2(C)[C@@H](OC(=O)[C@H]1O[C@]123)c4ccoc4)[C@@]56C
TargetLTR
SolubilityIn Vitro: DMSO : 100 mg/mL (194.34 mM)

Bioactivity

In Vivo
Nomilin attenuated blood-brain barrier (BBB) disruption in MCAO rats, which might be associated with alleviating the loss of tight junction proteins, including ZO-1 and occludin-5.
In Vitro
Nomilin treatment significantly mitigated cell death and decreased lactate dehydrogenase (LDH) release and ROS production in SH-SY5Y cells induced by oxygen-glucose deprivation (OGD), which was almost abolished by Nrf2 knockdown.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Nomilin

Similar Products

  • Nomilin [orb3127568]

    95.0%(HPLC)

    1063-77-0

    1 g
  • Nomilin [orb1303925]

    99.84% (May vary between batches)

    1063-77-0

    514.56

    C28H34O9

    5 mg, 10 mg, 50 mg, 100 mg, 25 mg, 1 ml x 10 mM (in DMSO)
  • Nomilin glucoside [orb1695876]

    123564-62-5

    694.72

    C34H46O15

    1 mg
  • Nomilin (Standard) [orb3140429]

    1063-77-0

    514.56

    C28H34O9

    10 mg
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.

Documents Download

Datasheet
Product Information
Download

Request a Document

Protocol Information

Nomilin (orb1222891)

  • Star
  • Star
  • Star
  • Star
  • Star
  • 0.0
Based on 0 reviews

Participating in our Biorbyt product reviews program enables you to support fellow scientists by sharing your firsthand experience with our products.

Login to Submit a Review

No reviews yet

Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

5 mg
$ 80.00
10 mg
$ 110.00
25 mg
$ 200.00
50 mg
$ 270.00
100 mg
$ 390.00
500 mg
$ 910.00