Notoginsenoside R1

SKU: orb1221774

Description

Notoginsenoside R1 has been shown to exhibit antioxidant, antiapoptotic, anti-inflammatory, and immune-stimulatory properties.

Images & Validation

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Key Properties

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CAS Number	80418-24-2
MW	933.13
Purity	>98% (HPLC)
Formula	C₄₇H₈₀O₁₈
SMILES	[C@@H]1([C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O)O[C@@](C)(CCC=C(C)C)[C@H]1CC[C@]2([C@@]3(C[C@@H]([C@H]4C([C@H](CC[C@@]4([C@H]3C[C@H]([C@H]12)O)C)O)(C)C)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O[C@H]1[C@@H]([C@H]([C@@H](CO1)O)O)O)C)C
Target	ERK1\| ERK2
Solubility	DMSO : ≥ 100 mg/mL; 107.17 mM

Bioactivity

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In Vivo	Animal model: Male Sprague-Dawley (SD) rats (200-250 g). Dosage: 5 mg/kg/h. Administration: Infused 20 min before LPS infusion via the right jugular vein. Result: Ameliorated the LPS-induced reduction in the mesenteric venular shear rate to some extent. Attenuated the LPS-induced adhesion of leukocytes to the venular wall. Inhibited mast cell degranulation and cytokine elevation. Read more...

Storage & Handling

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Storage	Storage temperature: -20°C. Stability: ≥ 2 years
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Sanchinoside R1 | Sanqi glucoside R1

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Gene Symbol

ERK1| ERK2

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