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Nrf2 activator 18

SKU: orb2814482

Description

Nrf2 activator 18 (Compound 11a) is an orally bioavailable small molecule that activates the Keap1/Nrf2/HO-1 pathway, leading to Nrf2 nuclear translocation and antioxidant response. It inhibits IL-6 release (IC50 = 4.816 µM) and has shown anti-inflammatory efficacy in a murine model of PM2.5-induced lung injury.

Research Area

Immunology & Inflammation

Images & Validation

Key Properties

MW377.45
FormulaC23H24FN3O
TargetNrf2,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Nrf2 activator 18 (orb2814482)

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