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NZ-804

SKU: orb2814230

Description

NZ-804 is an orally active inhibitor of the SARS-CoV-2 main protease (Mpro) with an IC50 of 8.9 nM. It inhibits replication of SARS-CoV-2 in HeLa-hACE2 cells, showing an EC50 of 14 nM. NZ-804 exhibits broad-spectrum antiviral activity against various CoVs and decreases viral replication in mice and hamster models.

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Key Properties

CAS Number2858658-44-1
MW469.56
FormulaC27H23N3O3S
SMILESO=C(C1=CN=CC=2C=CNC21)N3CCC(=C4C=5C=CC=CC5CS(=O)(=O)C=6C=CC=CC64)CC3

Storage & Handling

Storage-20°C
DisclaimerFor research use only
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NZ-804 (orb2814230)

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