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NZ-804

SKU: orb2814230

Description

NZ-804 is a potent, orally bioavailable inhibitor of the SARS-CoV-2 main protease (Mpro), demonstrating low nanomolar activity in vitro (IC50 8.9 nM; EC50 14 nM in HeLa-hACE2 cells). It shows broad-spectrum anti-coronavirus efficacy and has proven effective in reducing viral replication in mouse and hamster infection models.

Research Area

Infectious Disease & Virology

Images & Validation

Key Properties

CAS Number2858658-44-1
MW469.56
FormulaC27H23N3O3S
SMILESO=C(C1=CN=CC=2C=CNC21)N3CCC(=C4C=5C=CC=CC5CS(=O)(=O)C=6C=CC=CC64)CC3
TargetSARS-CoV,Virus Protease

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Protocol Information

NZ-804 (orb2814230)

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