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Oleonuezhenide

SKU: orb1297568

Description

Oleonuezhenide, a natural compound derived from Ligustrum lucidum, is a research chemical studied for its neuroprotective properties and potential anti-osteoporotic effects. In vitro and in vivo research explores its mechanisms in models of neurodegenerative diseases and bone metabolism.

Images & Validation

Key Properties

CAS Number112693-21-7
MW1073.01
Purity99.25% (May vary between batches)
FormulaC48H64O27
SMILESCOC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)\C(=C\C)[C@@H]1CC(=O)OC[C@H]1O[C@@H](OCCc2ccc(O)cc2)[C@H](OC(=O)C[C@H]2\C(=C/C)[C@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)OC=C2C(=O)OC)[C@@H](O)[C@@H]1O
TargetOthers
SolubilityDMSO:50 mg/mL (46.6 mM)

Bioactivity

In Vivo
In ovariectomized mice, administration of wedelolactone and oleonuezhenide prevented ovariectomy-induced bone loss by enhancing osteoblastic activity.
In Vitro
Oleonuezhenide elevated casein kinase 2-alpha (CK2α) expression, resulting in β-catenin and Runx2 nuclear translocation. Oleonuezhenide protects bone marrow mesenchymal stem cells by relieved wedelolactone-induced cytotoxicity and maintained osteoblastic activity.

Storage & Handling

Storagekeep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

inhibit, Ligustri, Oleonuezhenide, neuroprotective, Lucidi, Fructus, Inhibitor

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Key Properties

No computed properties available.

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Oleonuezhenide (orb1297568)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

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1 mg
$ 170.00
5 mg
$ 390.00
10 mg
$ 560.00
1 ml x 10 mM (in DMSO)
$ 620.00
25 mg
$ 870.00
50 mg
$ 1,130.00
DispatchUsually dispatched within 3-5 working days
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