Oleoylethanolamide

SKU: orb1309303

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Description

Oleoylethanolamide is a potent endogenous ligand for the PPAR-α receptor. It is widely used in metabolic and appetite regulation research, serving as a key tool for in vitro and in vivo studies of lipid sensing and energy homeostasis.

Research Area

Neuroscience

Images & Validation

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Key Properties

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CAS Number	111-58-0
MW	325.53
Purity	>98%
Formula	C₂₀H₃₉NO₂
SMILES	CCCCCCCC\C=C/CCCCCCCC(=O)NCCO
Target	GPCR
Solubility	Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 35 mg/ml)

Bioactivity

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In Vivo

Treatment with OEA (5 mg/kg/day, intraperitoneal injection, i.p.) significantly attenuated the progress of liver fibrosis in both two experimental animal models by blocking the activation of hepatic stellate cells (HSCs). Gene expression analysis of hepatic tissues indicated that OEA inhibited the expression of α-smooth muscle action (α-SMA) and collagen matrix, fibrosis markers, and genes involved in inflammation and extracellular matrix remodeling.

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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OEA; Oleylethanolamide

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Compound Identifiers

PubChem CID

5283454 ↗

Key Properties

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No computed properties available.

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