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Olmutinib (b)

SKU: orb1226469

Description

Olmutinib (HM61713, BI-1482694) is a pontent and T790M-specific third-generation EGFR inhibitor for treatment of NSCLC.Lung Cancer Phase 2 Clinical(In Vitro):Olmutinib potently inhibits EGFR in HCC827 cells expressing EGFRDEL19 (IC50=9.2 nM) and H1975 cells expressing EGFRL858R/T790M (IC50=10 nM). In contrast, the IC50 of olmutinib against cells expressing EGFRWT is 2225 nM.

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Key Properties

CAS Number1353550-13-6
MW486.5887
Purity>98% (HPLC)
FormulaC26H26N6O2S
SMILESCN1CCN(CC1)C2=CC=C(C=C2)NC3=NC4=C(C(=N3)OC5=CC=CC(=C5)NC(=O)C=C)SC=C4
TargetEGFR
SolubilityDMSO: ≥ 44 mg/mL

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

HM-61713 | BI-1482694
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Olmutinib (b) (orb1226469)

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500 mg
2 mg
$ 70.00
5 mg
$ 90.00
10 mg
$ 130.00
25 mg
$ 190.00
50 mg
$ 250.00
100 mg
$ 380.00
200 mg
$ 600.00