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OP-3136

SKU: orb3210857

Description

OP-3136 is a selective inhibitor of KAT6. It can reduce the proliferation capability of cancer cells and inhibit cell growth in ER+ breast cancer cell models with KAT6 overexpression. When used in combination with ER antagonists/degraders or CDK4/6 inhibitors, OP-3136 exhibits synergistic anti-tumor activity in mouse xenograft models. It is applicable in research related to HR+/HER2- breast cancer.

Images & Validation

Key Properties

CAS Number3056105-63-3
MW462.48
FormulaC20H22N4O7S
SMILESO=C(NS(=O)(=O)C=1C(OC)=CC(OC)=CC1OC)C2=NC(OC)=C(C=C2)CN3N=CC=C3
TargetHistone Acetyltransferase,Estrogen Receptor/ERR,CDK

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information