Ouabain octahydrate

SKU: orb1745280

Description

Ouabain octahydrate (Acocantherine) is a cardiac glycoside that inhibits Na(+)/K(+) ATPase. Ouabain octahydrate regulates transcription of MDR (increase, Pgp) and MRP (increase MRP1 and decrease CFTR, cyctic fibrosis transport receptor or cAMP-activated Cl- channel) genes, also alters localization of MRP1.

Research Area

Cell Biology, Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number	11018-89-6
MW	728.77
Purity	98.00%
Formula	C₂₉H₄₄O₁₂·8H₂O
SMILES	O.O.O.O.O.O.O.O.CC1OC(OC2CC(O)C3(CO)C4C(O)CC5(C)C(CCC5(O)C4CCC3(O)C2)C2=CC(=O)OC2)C(O)C(O)C1O
Target	ATPase,Autophagy

Storage & Handling

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Storage	-20°C
Disclaimer	For research use only

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Gene Symbol

ATPase,Autophagy

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