Oxidopamine hydrochloride

SKU: orb1309284

Description

Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride) is a selective dopaminergic neurotoxin that induces inflammation via COX-2 activation. It is extensively used to model Parkinson's disease pathology in vivo and to study neuroinflammation and neuronal death in vitro.

Research Area

Cell Biology, Neuroscience, Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number	28094-15-7
MW	205.64
Purity	99.85% (May vary between batches)
Formula	C₈H₁₂ClNO₃
SMILES	Cl.NCCc1cc(O)c(O)cc1O
Target	Autophagy,Mitophagy,Dopamine Receptor
Solubility	10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (9.73 mM);H2O:62.49 mg/mL (303.88 mM);DMSO:62.49 mg/mL (303.88 mM)

Storage & Handling

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Storage	store under nitrogen \| Powder: -20°C for 3 years \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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p38 MAPK, Oxidopamine, Oxidopamine hydrochloride, Oxidopamine Hydrochloride, p-p38, PGE synthase, PGE2, SH-SY5Y cells, Prostaglandin E synthase, 6-OHDA, 6-OHDA Hydrochloride, 6-OHDA hydrochloride, 6-Hydroxydopamine, 6-Hydroxydopamine Hydrochloride, 6-Hydroxydopamine hydrochloride, Autophagy, attention-deficit hyperactivity disorder, Apoptosis, Caspase, Dopamine Receptor, dopamine, DopamineReceptor, COX, Cyclooxygenase, Mitochondrial Autophagy, PC12 cells, Parkinson's disease, Neuro-2a cells, neurotoxicity, Mitophagy, inhibit, Lesch-Nyhan syndrome, Interleukin Related, Inhibitor

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Compound Identifiers

PubChem CID

160157 ↗

Key Properties

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No computed properties available.

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