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Palmatine

SKU: orb1301320

Description

Palmatine (Burasaine) is a natural alkaloid with research applications in neuroscience as a dopamine synthesis inhibitor and in virology for potential anti-flaviviral activity. It is also investigated in models of liver disease, inflammation, and hypertension, based on its traditional medicinal uses.

Research Area

Cell Biology, Epigenetics & Chromatin, Infectious Disease & Virology, Metabolism Research, Neuroscience

Images & Validation

Key Properties

CAS Number3486-67-7
MW352.4
Purity99.49%
FormulaC21H22NO4
SMILESCOc1cc2CC[n+]3cc4c(OC)c(OC)ccc4cc3-c2cc1OC
TargetAChR,Virus Protease,Aurora Kinase,Antibacterial,Indoleamine 2,3-Dioxygenase (IDO),IDO,Parasite,Cholinesterase (ChE),Apoptosis
SolubilityDMSO:16.5 mg/mL (46.82 mM)

Bioactivity

Target IC50
BChE:6.84 μM|IDO1:157 μM (rhIDO-1)|IDO1:3 μM (HEK 293-hIDO-1)|AChE:0.51 μM|WNV NS2B-NS3:96 μM

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Berbericinine, colitis, Crohn's disease, AChE, BChE, Burasaine, Apoptosis, Aurora Kinase, AuroraKinase, Palmatine, Inflammatory bowel disease, Indoleamine 2,3Dioxygenase (IDO), Indoleamine 2,3-Dioxygenase (IDO), Indoleamine2,3Dioxygenase(IDO), Indoleamine2,3Dioxygenase, Indoleamine 2,3-Dioxygenase, Inhibitor, inhibit, NS2B-NS3, IDO, IDO-1, IBD, memory-enhancing, fulminant hepatic failure, West Nile virus, Virus Protease, ulcerative

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Key Properties

No computed properties available.

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Palmatine (orb1301320)

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% DMSO +
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% Tween 80 +
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Available Sizes

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50 mg
$ 70.00
100 mg
$ 80.00
1 ml x 10 mM (in DMSO)
$ 90.00
500 mg
$ 110.00
1 g
$ 130.00
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