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PAT-048

SKU: orb1706845

Description

PAT-048 is a potent and selective autotaxin inhibitor (IC50=20 nM) shown to reduce dermal fibrosis in vivo and suppress IL-6 mRNA. It is a valuable research tool for studying lysophosphatidic acid (LPA) signaling in fibrotic diseases, including skin and lung fibrosis models.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number1359983-15-5
MW461.91
FormulaC22H18ClF2N3O2S
SMILESCC=1N(C=2C(C1SC3=C(F)C(C(O)=O)=CC=C3)=CC=C(Cl)C2F)C4=CN(CCC)N=C4
TargetPDE

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Protocol Information

PAT-048 (orb1706845)

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