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PBS-1086

SKU: orb1738333

Description

PBS-1086 is a novel small molecule that dually inhibits canonical and noncanonical NF-κB signaling. It enhances and prolongs the initial response to EGFR inhibitors in NSCLC models and suppresses the PDHK1-PDHA1 axis in PTEN-deficient cells, applicable for in vitro and in vivo cancer research.

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Key Properties

CAS Number1246668-32-5
MW312.28
FormulaC16H12N2O5
SMILESOC1C2C(O2)C(=O)C=C1NC(=O)C3=CC=4C(NC3=O)=CC=CC4
TargetOthers

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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PBS-1086 (orb1738333)

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