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PD-1/PD-L1-IN-51

SKU: orb2665064

Description

PD-1/PD-L1-IN-51 (Compound III-4) is a potent small-molecule inhibitor that directly targets PD-L1 with an IC50 of 2.9 nM, effectively blocking the PD-1/PD-L1 interaction to restore T-cell function and enhance IFN-γ production. This mechanism supports its application in cancer immunotherapy research, demonstrating antitumor activity in both cellular assays and in vivo models.

Research Area

Cell Biology, Immunology & Inflammation

Images & Validation

Key Properties

TargetPD-1/PD-L1

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information

PD-1/PD-L1-IN-51 (orb2665064)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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