Pentagalloylglucose

SKU: orb1303737

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Description

1,2,3,4,6-Penta-O-galloyl-β-D-glucose (PGG) is a bioactive polyphenol with diverse pharmacological activities. It exhibits antimutagenic, antioxidant, anti-inflammatory, and anti-proliferative properties, and shows potential in metabolic, cardiovascular, antiviral, and antiparasitic research. Studies indicate its efficacy in both in vitro and in vivo models for conditions like diabetes, hepatitis B, and Chagas disease.

Research Area

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Infectious Disease & Virology, Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

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Key Properties

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CAS Number	14937-32-7
MW	940.68
Purity	99.72% (May vary between batches)
Formula	C₄₁H₃₂O₂₆
SMILES	Oc1cc(cc(O)c1O)C(=O)OC[C@H]1O[C@@H](OC(=O)c2cc(O)c(O)c(O)c2)[C@H](OC(=O)c2cc(O)c(O)c(O)c2)[C@@H](OC(=O)c2cc(O)c(O)c(O)c2)[C@@H]1OC(=O)c1cc(O)c(O)c(O)c1
Target	Influenza Virus,ROS,Reactive Oxygen Species,JAK,Apoptosis,Wnt/beta-catenin,Nrf2
Solubility	5% DMSO+95% Saline:5 mg/mL (5.32 mM);DMSO:142 mg/mL (150.95 mM)

Bioactivity

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Target IC50	HT29 cells:28 μg/mL\|NCM460 cells:23 μg/mL\|HepG2 cells:92.4 μM\|MDA-MB-231 cells:9.12 μM\|HeLa cells:356.3 μM\|TE-671 cells:> 10 μg/mL (ED50)\|HCT116 cells:1.61 μM Read more...

Storage & Handling

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Storage	store at low temperature,keep away from direct sunlight \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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1,2,3,4,6-O-Pentagalloylglucose, 1,2,3,4,6-Pentagalloyl glucose, 1,2,3,4,6-Penta-O-galloyl-b-D-glucopyranose, 1,2,3,4,6-Penta-O-galloyl-beta-D-glucopyranose, 1,2,3,4,6-Penta-O-galloyl-β-D-glucopyranose, inhibit, InfluenzaVirus, Influenza Virus, Inhibitor, Penta-O-galloyl-b-D-glucose, Penta-O-galloyl-beta-D-glucose, Penta-O-galloyl-β-D-glucose, Pentagalloylglucose

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Compound Identifiers

PubChem CID

65238 ↗

Key Properties

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No computed properties available.

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