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PF-06827443

SKU: orb1699656

Description

PF-06827443 is an orally administered, brain-penetrant positive allosteric modulator (PAM) that exhibits high selectivity for the M1 muscarinic acetylcholine receptor with negligible intrinsic agonist activity. It is a valuable research tool for investigating M1 receptor function in both in vitro assays and in vivo models relevant to cognitive disorders.

Research Area

Neuroscience

Images & Validation

Key Properties

MW404.47
FormulaC24H24N2O4
SMILESO=C1N([C@@H]2[C@@H](O)COCC2)CC3=C1C=C(CC4=CC=C(C5=COC=N5)C=C4)C(C)=C3
TargetAChR,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information