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PF-07957472

SKU: orb2665015

Description

PF-07957472 (Compound 4) is a potent, orally bioavailable inhibitor of the SARS-CoV-2 papain-like protease (PLpro). It demonstrates antiviral activity with an EC50 of 13.9 nM in infected NHBE cells and has shown efficacy in a mouse-adapted COVID-19 infection model, supporting its use for in vitro and in vivo antiviral research.

Research Area

Infectious Disease & Virology

Images & Validation

Key Properties

CAS Number3041047-51-9
MW480.60
FormulaC29H32N6O
SMILESO=C(NC1(C=2C=C(N=C3C=CC=CC32)C=4C=NN(C4)C)CC1)C5=CC(=CC=C5C)N6CCN(C)CC6
TargetVirus Protease,SARS-CoV

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Protocol Information

PF-07957472 (orb2665015)

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