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Phanginin A

SKU: orb1744452

Description

Phanginin A, a natural product discovered in Caesalpinia sappan Linn, activates SIK1 and inhibits gluconeogenesis in mouse primary hepatocytes. Phanginin A increases PDE4 activity and suppresses the hepatic cAMP/PKA/CREB pathway, improving metabolic disorders in ob/ob mice. It may be used in studies of type 2 diabetes.

Images & Validation

Key Properties

CAS Number1011528-58-7
MW360.44
Purity95.54%
FormulaC21H28O5
SMILESO[C@H]1[C@@]23[C@]([C@@](C(OC)=O)(CO1)CCC2)(CC[C@@]4([C@@]3(CC5=C([C@@H]4C)C=CO5)[H])[H])[H]
TargetSIK

Storage & Handling

Storage-20°C
DisclaimerFor research use only
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Phanginin A (orb1744452)

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100 mg
5 mg
$ 1,500.00
10 mg
$ 1,930.00