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Phorbol

SKU: orb1303269

Description

Phorbol (4β-Phorbol) is a diterpenoid natural product known for its potent tumor-promoting activity, which it exerts by directly activating Protein Kinase C (PKC). It is extensively used as a research tool in both in vitro and in vivo studies to investigate PKC signaling pathways, cellular proliferation, and carcinogenesis mechanisms.

Research Area

Epigenetics & Chromatin, Signal Transduction

Images & Validation

Key Properties

CAS Number17673-25-5
MW364.43
Purity98.87%
FormulaC20H28O6
SMILESC[C@@H]1[C@@H](O)[C@]2(O)[C@H]([C@@H]3C=C(CO)C[C@@]4(O)[C@@H](C=C(C)C4=O)[C@@]13O)C2(C)C
TargetPKC
SolubilityDMSO:50 mg/mL (137.2 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.74 mM)

Storage & Handling

Storagekeep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

(+)-Phorbol, 4β-Phorbol, 4b-Phorbol, 4beta-Phorbol, Phorbol, PKC

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Key Properties

No computed properties available.

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Protocol Information

Phorbol (orb1303269)

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Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

2 mg
$ 80.00
5 mg
$ 100.00
1 ml x 10 mM (in DMSO)
$ 110.00
10 mg
$ 120.00
25 mg
$ 170.00