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Physalin H

SKU: orb1681903

Description

Physalin H is a Hedgehog signaling inhibitor that blocks GLI1-DNA complex formation and exhibits quinone reductase induction. It demonstrates immunosuppressive effects on T cells in vitro and in vivo, along with cytotoxic activity against various cancer cell lines and leishmanicidal activity against Leishmania major promastigotes.

Research Area

Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Metabolism Research, Pharmacology & Drug Discovery, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number70241-09-7
MW562.99
FormulaC28H31ClO10
SMILESC[C@]12[C@]34[C@]5([C@@]6(C)[C@@](CO[C@](O3)(C5=O)[C@]7([C@](CC[C@@]4(O)C(=O)O1)([C@]8(C)[C@@](Cl)([C@H](O)C7)CC=CC8=O)[H])[H])(C(=O)O[C@@H]2C6)[H])[H]
TargetAutophagy,Antifection,gp120/CD4,Hedgehog/Smoothened,Endogenous Metabolite

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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Physalin H (orb1681903)

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