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PI3K/AKT-IN-4

SKU: orb2663450

Description

PI3K/AKT-IN-4 is a natural diterpenoid that inhibits hepatocellular carcinoma cell proliferation (IC50=4.72 μM in Hep3B cells) by inducing apoptosis, cell cycle arrest, and oxidative stress. Its antitumor mechanism involves suppressing the PI3K/Akt pathway and targeting PARP1 and CDK2, making it a useful probe for oncology and signaling pathway research.

Research Area

Cell Biology, Epigenetics & Chromatin, Molecular Biology, Signal Transduction

Images & Validation

Key Properties

MW286.41
FormulaC19H26O2
TargetCDK,Akt,PI3K,PARP,Apoptosis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information

PI3K/AKT-IN-4 (orb2663450)

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