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PM226

SKU: orb1692564

Description

This potent and selective CB2 receptor agonist (Ki = 12.8 nM; EC50 = 38.67 nM) exhibits negligible CB1 affinity. It is BBB-permeable and demonstrates anti-inflammatory and neuroprotective effects, such as suppressing microglial activation in an EAE mouse model of multiple sclerosis, making it a valuable research tool for studying neuroinflammation.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number1949726-13-9
MW357.49
FormulaC22H31NO3
SMILESO(C)C1=C2C3=C(C(C)(C)OC2=CC(C(CCCCCC)(C)C)=C1)C=NO3
TargetOthers,Cannabinoid Receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Protocol Information

PM226 (orb1692564)

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