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Podocarpic acid

SKU: orb1309225

Description

Podocarpic acid is a natural diterpenoid that acts as a selective TRPA1 channel activator. It is utilized in pharmacological research to study pain, inflammation, and neurogenic responses in both cellular and animal models.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number5947-49-9
MW274.35
Purity99.67% (May vary between batches)
FormulaC17H22O3
SMILES[H][C@@]12CCc3ccc(O)cc3[C@@]1(C)CCC[C@]2(C)C(O)=O
TargetTRP/TRPV Channel
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (14.58 mM);DMSO:100 mg/mL (364.5 mM)

Bioactivity

In Vivo
Podocarpic acid and LA alleviate the Podocarpic acidthogenic phenotypes of glod-4 animals by reverting the high endogenous MGO and GO to almost wild-type-like levels.
In Vitro
Podocarpic acid activates SKN-1 in C. elegans, similar to known Nrf2 activators such as α-lipoic acid (LA).

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Transient receptor potential channels, TRP Channel, TRPV Channel, TRPA1, TRPChannel, TRPVChannel, Podocarpic acid, inhibit, Inhibitor
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Quality Guarantee

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Key Properties

No computed properties available.

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Protocol Information

Podocarpic acid (orb1309225)

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5 mg
$ 80.00
10 mg
$ 100.00
25 mg
$ 140.00
50 mg
$ 190.00
100 mg
$ 250.00
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