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Poliumoside

SKU: orb1221647

Description

Poliumoside is a natural compound which exhibits significant inhibition of advanced glycation end product formation with IC50 value of 4.6-25.7 μM, it also exhibits great inhibitory effects on rat lens aldose reductase with IC50 values of 0.85 μM.Poliumoside has oxidant scavenging, antibacterial and hemostasis capacities, it can inhibit Biofilm-forming Staphylococcus aureus in mice.

Images & Validation

Key Properties

CAS Number94079-81-9
MW770.73
Purity>98% (HPLC)
FormulaC35H46O19
SMILESOc1ccc(cc1O)/C=C/C(=O)O[C@@H]5[C@@H](CO[C@@H]2O[C@@H](C)[C@H](O)[C@@H](O)[C@H]2O)O[C@@H](OCCc3ccc(O)c(O)c3)[C@H](O)[C@H]5O[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O)[C@H]4O
TargetAntifungal
SolubilityIn Vitro: DMSO : 100 mg/mL (129.75 mM)

Bioactivity

In Vivo
Poliumoside inhibits vessel dilation in larval zebrafish.
In Vitro
Poliumoside inhibits AGE formation and RLAR, with IC50s of 19.69, and 8.47 μM, respectively. Poliumoside (5-30 μM; 3 h) inhibits AAPH-induced hemolysis of rat red blood cells in vitro. Poliumoside (12.5-100 μM; pretreated 2 h) inhibits the release of TNF-α and IL-6 in LPS-induced RAW 264.7 cells.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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  • Poliumoside [orb1300156]

    99.80% (May vary between batches)

    94079-81-9

    770.73

    C35H46O19

    100 mg, 10 mg, 50 mg, 1 mg, 5 mg, 25 mg, 1 ml x 10 mM (in DMSO), 200 mg, 2 mg
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Protocol Information

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200 mg
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5 mg
$ 190.00
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$ 520.00
50 mg
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100 mg
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