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Prosaikogenin G

SKU: orb1296862

Description

Prosaikogenin G is a bioactive metabolite of Saikosaponin d, isolated from Bupleurum bicaule. It has demonstrated significant in vitro inhibition of angiotensin II-induced mesangial cell proliferation, making it a candidate for research in renal fibrosis and cardiovascular pathophysiology.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number99365-23-8
MW618.84
Purity99.42%
FormulaC36H58O8
SMILES[H][C@@]12CC(C)(C)CC[C@@]11CO[C@@]22C=C[C@]3([H])[C@@]4(C)CC[C@@H](O[C@@H]5O[C@H](C)[C@H](O)[C@H](O)[C@H]5O)[C@](C)(CO)[C@]4([H])CC[C@@]3(C)[C@]2(C)C[C@@H]1O
TargetRAAS

Bioactivity

In Vitro
Prosaikogenin G holds a protective effect on the kidney for their down-regulated activity to angiotensin II (1 μM)-induced rat mesangial cell line (MC) proliferation at contentration of 25 or 50 μM, and does not rendered injury to the normal MC .

Storage & Handling

Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

inhibit, Inhibitor, Angiotensin II, Prosaikogenin G
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Key Properties

No computed properties available.

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Protocol Information

Prosaikogenin G (orb1296862)

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1 mg
$ 140.00
2 mg
$ 190.00
5 mg
$ 300.00
10 mg
$ 420.00
25 mg
$ 670.00
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