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Prostaglandin E2 Inhibitor 3

SKU: orb1980031

Description

This small molecule is a selective mPGES-1 inhibitor (IC50 = 0.2 µM) that reduces PGE2, IL-6, and 5-LO products in cellular assays and shows in vivo efficacy by inhibiting leukocyte infiltration in a murine peritonitis model at 10 mg/kg, supporting research on inflammation and related pathways.

Images & Validation

Key Properties

MW452.32
FormulaC21H14BrN3O2S
SMILESO=C(C1=CC=CC=C1Br)NC2=NN=C(C3=CC=C(C4=CC(O)=CC=C4)C=C3)S2
TargetOthers

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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Prostaglandin E2 Inhibitor 3 (orb1980031)

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Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

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