PROTAC BTK Degrader-6

SKU: orb2278408

Description

PROTAC BTK Degrader-6 (Compound 15) is a potent degrader (DC50 = 3.18 nM) that demonstrates anti-inflammatory activity through NF-κB pathway inhibition and reduction of IL-1β and IL-6. This molecule is a valuable chemical tool for investigating BTK-related immunology and inflammation in both cellular and animal models.

Research Area

Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

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Key Properties

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CAS Number	2767204-39-5
MW	837.92
Formula	C₄₅H₄₇N₁₁O₆
SMILES	NC1=C2C(=NN(C2=NC=N1)C3CCN(C(CN4CCN(CC5CN(C5)C=6C=C7C(=CC6)C(=O)N(C7=O)C8C(=O)NC(=O)CC8)CC4)=O)CC3)C9=CC=C(OC%10=CC=CC=C%10)C=C9
Target	PROTACs,BTK

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

168476120 ↗

Key Properties

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No computed properties available.

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