Cart summary

You have no items in your shopping cart.

PROTAC CDK9 degrader-2

SKU: orb1988544

Description

PROTAC CDK9 degrader-2 (compounds 11c) is a potent and selective CDK9-targeting PROTAC with an IC50 of 17 μM in MCF-7 cells. It is constructed by linking a CDK9 ligand to the natural product Wogonin, which binds the E3 ligase CRBN. This molecule is a useful chemical tool for studying CDK9 biology and targeted protein degradation in cancer research models.

Research Area

Cell Biology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2435721-30-3
MW748.74
FormulaC39H36N6O10
SMILESO=C(C=C(C1=CC=CC=C1)O2)C3=C2C(OCC4=CN(CCCCCCCC(NC5=C(C(N(C6C(NC(CC6)=O)=O)C7=O)=O)C7=CC=C5)=O)N=N4)=C(O)C=C3O
TargetCDK,Others,PROTACs

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Similar Products

  • CDK9-IN-10 [orb1710106]

    99.80% (May vary between batches)

    3542-63-0

    360.36

    C22H16O5

    5 mg, 10 mg, 25 mg, 50 mg, 2 mg
  • PROTAC CDK9/CycT1 Degrader-2 [orb2277574]

    612.76

    C30H36N4O6S2

    50 mg, 5 mg
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.

Key Properties

No computed properties available.

Documents Download

Datasheet
Product Information
Download

Request a Document

Protocol Information

PROTAC CDK9 degrader-2 (orb1988544)

  • Star
  • Star
  • Star
  • Star
  • Star
  • 0.0
Based on 0 reviews

Participating in our Biorbyt product reviews program enables you to support fellow scientists by sharing your firsthand experience with our products.

Login to Submit a Review

No reviews yet

Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO +
%+
% Tween 80 +
%