PROTAC FSP1 degrader 1

SKU: orb3174549

Description

PROTACFSP1 degrader 1 is an effective and selective PROTAC degrader that targets FSP1. It significantly induces the accumulation of lipid peroxides within cells. Additionally, PROTACFSP1 degrader 1 works synergistically with GPX4 inhibitors to enhance ferroptosis. It increases the mRNA expression of ferroptosis-related proteins (GPX4, FTH1, ACSL4, TfR1, FSP1) and is instrumental in the study of triple-negative breast cancer.

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Key Properties

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CAS Number	3096510-51-6
MW	749.79
Formula	C₄₁H₃₅N₉O₆
SMILES	N#CC=1C2=NC=3C=CC=CC3N2C(NC(=O)CC(=O)NCCCCCNC4=CC=CC=5C(=O)N(C(=O)C45)C6C(=O)NC(=O)CC6)=C(C#N)C1C7=CC=C(C=C7)C
Target	Ferroptosis,Glutathione Peroxidase

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

Ferroptosis,Glutathione Peroxidase

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