Queen's Award Received in 2021 ISO 9001 Certified Delivered over 1,000,000 bio-reagents to life science researchers Trusted by Life Science Communities
Cart summary

You have no items in your shopping cart.

PROTAC SARS-CoV-2 Mpro degrader-5

SKU: orb3210367

Description

PROTAC SARS-CoV-2 Mpro degrader-5 is a PROTAC compound targeting the main protease (Mpro) of SARS-CoV-2. It binds the CRBN E3 ubiquitin ligase to form a ternary complex with SARS-CoV-2 Mpro, inducing K48-linked polyubiquitination. This process drives proteasome-dependent degradation of SARS-CoV-2 Mpro with a high selectivity index (CC50/DC50 > 10) in human embryonic kidney cells. PROTAC SARS-CoV-2 Mpro degrader-5 is valuable for research related to COVID-19.

Images & Validation

Key Properties

TargetSARS-CoV,Virus Protease,PROTACs

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.

Protocol Information