PROTAC TYK2 degrader-1

SKU: orb2565415

Description

PROTAC TYK2 degrader-1 (CPD-155) is a selective, heterobifunctional degrader that recruits the VHL E3 ligase to induce TYK2 degradation with >60% Dmax. This tool compound enables the investigation of TYK2 biology and its therapeutic potential in autoimmune and inflammatory disease models, both in vitro and in vivo.

Research Area

Cardiovascular Research, Epigenetics & Chromatin, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

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Key Properties

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CAS Number	2770470-20-5
MW	815.84
Formula	C₄₀H₄₁N₁₃O₇
SMILES	O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2NCCCCCNC(=O)C=4C=CC(NC5=CC(NC6=C(OC)C(=CC=C6)C=7N=CN(C)N7)=C(C(NC)=O)N=N5)=NC4
Target	JAK,PROTACs

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

169087170 ↗

Key Properties

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No computed properties available.

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