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PSB-KK1445

SKU: orb2646051

Description

PSB-KK1445 is a potent and selective agonist of GPR18, exhibiting EC50 values of 45.4 nM for humans and 124 nM for mice. The selectivity of PSB-KK1445 for GPR18 over the CB receptor subtypes GPR55 and GPR183 exceeds 200-fold.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number885896-54-8
MW446.48
FormulaC24H23FN6O2
SMILESO=C1C2=C(N=C(NCCC3=CNC=4C=CC=CC43)N2CC5=CC=C(F)C=C5)N(C(=O)N1C)C
TargetCannabinoid Receptor

Storage & Handling

Storage-20°C
DisclaimerFor research use only
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PSB-KK1445 (orb2646051)

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